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Protein Purification System

Protein Purification System

  • Product Number:LD-PF10
  • Product Difference:A compact protein chromatography system for purifying proteins from microgram to gram scale

Product Introduction

The Compact Protein Purification System is a small, compact protein chromatography system that integrates and condenses the system while ensuring the precision of the piston pump, detector, and switching valve. With a footprint of just 250mm × 430mm, it enables efficient utilization of bench and refrigerator space, allowing researchers to easily perform routine protein purification.

The Protein Purification System is an intelligent, multi-purpose purification platform. Beyond proteins, it rapidly purifies diverse biomolecules including polysaccharides, peptides, oligonucleotides, nucleic acid vaccines, viruses, and natural small molecules. It accommodates protein purification from microgram to gram-scale quantities.

The modular protein purification system offers three flow rate configurations: LD-PF10®-10, LD-PF10®-100, and LD-PF10®-Pilot. These configurations suit R&D at various scales, process development studies, and small-scale to pilot-scale production. Applications span food science, biomedical research, agriculture, feed industry, pharmaceuticals, and environmental science.

Product Features

  • For temperature-sensitive samples, the compact protein purification system facilitates easy transport between laboratories and chromatography refrigerators without occupying significant space.

  • The system consists of a main unit and PPSN software. PPSN software requires no specialized programming skills, making chromatography method creation straightforward. PPSN software enables intuitive and flexible method creation, system control, and result analysis.

  • With a mature design and stable operation, it ensures continuous and reliable protein purification processes. Used in conjunction with chromatography columns and chromatography media, it addresses purification challenges across diverse applications.

Product parameters

System Main UnitPower supply: 100–240 V AC, 50–60 Hz; Dimensions: 250 × 430 × 330 mm; Weight: 15 kg
Chromatography System Pump

3-plunger pump, 0.01-50 mL/min, accuracy ≤±2%, precision RSD <1%

Single pump with dual inlet, low-pressure gradient mixing, gradient accuracy ≤±3% (0.1-50 mL/min, 5-95% B range)

Inlet Selection Valve6-in-1-out rotary valve, expandable to 6 A-line inlets (optional)
Pressure MonitorMonitors system pressure with a detection range of 0-1.0 MPa and a fluctuation range of ±10% FS
Autosampler Valve7-position rotary valve integrating loading, injection, and waste functions
Single-wavelength UV detector280nm, LED light source, detection range ±5mAU, resolution 0.01mAU, linearity ±5% (0-2AU), drift ≤10⁻³AU/h, noise ≤0.1mAU
Conductivity Detector

Range: 0-1000.00 mS/cm, Accuracy: ±0.01 mS/cm or ±2%, whichever is greater

Integrated temperature sensor with temperature compensation, temperature accuracy ±1°C

pH DetectorRange 0-14.00, Accuracy ±0.1 pH units (within pH 2-12 range) (Optional)
Back Pressure ValveProvides approximately 0.2 MPa pressure in the system flow path to prevent bubbles from forming in the mobile phase (optional)
Fully Automatic Sample Collector

Standard configuration includes a rack for 100 collection tubes, with a maximum capacity of 15mL per tube

Optional racks compatible with 2mL, 25mL, or 500mL collection tubes (optional)

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